If you are dependent on daily medication (Proton Pump Inhibitor Pills, also known as PPIs, such as Nexium®, Prilosec® and Prevacid®) to treat your acid reflux symptoms, the Enteryx Procedure may be a welcome alternative.

A less invasive alternative to surgery - performed as an outpatient procedure
Patients have been treated since 1999
In a clinical study, 81 patients followed to one year showed the following results*:

Demonstrated improvement in overall quality of life
70.4% of patients eliminated PPI use
An additional 9.9% of patients reduced daily medication by 50% or more
No serious adverse events

The Enteryx® Procedure

Upper Digestive System
At the lower end of your esophagus is a muscle ring called the LED (lower esophageal sphincter) which acts like a valve to allow foods and liquids to pass through to the stomach.

Acid Reflux Disease
When the LES works improperly, it allows stomach acids and contents to reflux back up into the esophagus, which may cause the burning sensation of heartburn.

Enteryx Procedure
The physician will pass an endoscope through your mouth and down into your esophagus.

Using a small needle, the physician will inject approximately one teaspoonful (6ml) of the Enteryx solution into your LES.

Body Response
Once injected, the Enteryx solution forms into a spongy, permanent implant and cannot be removed.

Based on observations in animal studies, the Enteryx solution is designed to encapsulate over time through a localized foreign body response.

Post-Procedure
Enteryx is designed to work with the body's own tissue by helping the LES form a more effective reflux barrier.

What Can You Expect After the Procedure?

Following the Enteryx Procedure, you may experience some of the following effects:

• Mild-to-moderate chest pain
• Difficulty swallowing
• A garlic smell on breath and body
• Sore throat
• Low-grade fever
• More gas

In a clinical trial of 85 patients, all of the above effects resolved without incident, usually within a timeframe from 2-3 days to 2 weeks.

Your physician may recommend a soft food and liquid diet for 2 to 3 days, and continuation of PPI therapy for a short period (e.g. 10 days) following the procedure. In addition, your physician may prescribe a pain reliever upon discharge.

Is the Enteryx Procedure right for you?

For many patients, the Enteryx Procedure has the potential to offer an effective treatment alternative for the symptoms of GERD.

You may be a candidate if:

You seek an alternative to the cost, inconvenience or side effects of daily medication. Your GERD symptoms can be managed with daily PPI medication.

To determine if the Enteryx Procedure may be right for you, please consult your physician.